Fourth on the Ligue 1 table ahead of the final round of games on Saturday, Kamaldeen's Stade Rennes, currently in a Europa League qualification spot, go into their clash with Lille knowing a win will be all but enough to instead secure them a Champions League spot should Monaco or Marseille lose on the day.
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Alexander Djiku – Marseille vs Strasbourg
Currently fifth on the Ligue 1 table, Djiku's Strasbourg must beat Marseille at all cost should they want to avoid a situation of potentially losing their Europa Conference League spot to Nice or Lens on the final matchday.
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Thomas Partey – Arsenal vs Everton
To qualify for the Champions League next season, Partey's Arsenal must beat Everton in the Premier League on Sunday while hoping that Tottenham Hotspur, who are currently fourth on standings, lose at Norwich City.
Partey, though, is not expected to play due to injury.
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Jordan Ayew, Jeffrey Schlupp and Jesurun Rak-Sakyi – Crystal Palace vs Manchester United
Hoping to play in the Europa League next season, Manchester United must beat Crystal Palace as a defeat will prove costly should West Ham United edge Tariq Lamptey's Brighton and Hove Albion.
Thus, Ayew, Schlupp and youngster Rak-Sakyi have a big game on their hands against the Red Devils.